Department of Pathology and Laboratory Medicine

Rebecca Baergen, MD

Polydorides AD, Kalish RB, Witkin SS, Baergen RN: Fetal Polymorphisms in anti-inflammatory cytokine and beta-adrenergic receptor genes associated with placental pathological lesions. Int J Gynecol Pathol 27: 79-85, 2008.

Heller DS, Faye-Petersen OM, Baergen R, Kaplan C: Handling of perinatal specimens-A society for pediatric pathology practice committee survey. Pediatr Dev Pathol 31:1, 2009.

Ethel Cesarman, MD, PhD

Mark T, Jayabalan D, Coleman M, Pearse RN, Wang YL, Lent R, Christos PJ, Lee JW, Agrawal YP, Matthew S, Ely S, Mazumdar M, Cesarman E, Leonard JP, Furman RR, Chen-Kiang S, Niesvizky R: Atypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma. Br J Haematol 143:654-660, 2008.

Czuchlewski DR, Csernus B, Bubman D, Hyjek E, Martin P, Chadburn A, Knowles DM, Cesarman E: Expression of the Follicular Lymphoma Variant Translocation 1 Gene in Diffuse Large B-Cell Lymphoma Correlates With Subtype and Clinical Outcome. Am J Clin Pathol 130:957-62, 2008.

Horenstein MG, Moontasri NJ, Cesarman E. The pathobiology of Kaposi's sarcoma: advances since the onset of the AIDS epidemic. J Cutan Pathol 35 Suppl 2:40-4, 2008.

Carbone A, Cesarman E, Spina M, Gloghini A, Schulz TF: HIV-associated lymphomas and gamma-herpesviruses. Blood 113:1213-1224, 2008.

Raphaël M, Said J, Borisch B, Cesarman E, Harris NL: Lymphomas associated with HIV infection. Pages: 340-342. In: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. (Eds). Fourth Edition. IARC Press, Lyon, France, 2008.

Said J, Cesarman E: Primary effusion lymphoma. In: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. (Eds). Fourth Edition. IARC Press, Lyon, France, 2008.

Lu P, Yang C, Guasparri I, Harrington W, Wang YL, Cesarman E: Early events of B-cell receptor signaling are not essential for the proliferation and viability of AIDS-related lymphoma [Letter to the Editor]. Leukemia 23:807-810, 2009.

Chadburn A, Hyjek EM, Tam W, Liu Y, Rengifo T, Cesarman E, Knowles DM: Immunophenotypic analysis of the Kaposi sarcoma herpesvirus (KSHV; HHV-8)-infected B cells in HIV+ multicentric Castleman disease (MCD). Histopathol 53:513-524, 2008.

Di Bartolo DL, Hyjek E, Keller S, Deng H, Guasparri I, Sun R, Chadburn A, Knowles DM, Cesarman E: Role of defective Oct-2 and OCA-B expression in immunoglobulin production and KSHV lytic reactivation in primary effusion lymphoma. J Virol 83:4315, 2009.

Ma Q, Cavallin LE, Yan B, Zhu S, Duran EM, Wang H, Hale LP, Dong C, Cesarman E, Mesri EA, Goldschmidt-Clermont PJ: Anti tumorigenicity of anti-oxidants in a transgenic Rac1 model of Kaposi’s sarcoma. Proc Natl Acad Sci 106:8683-8688, 2009.

A review of human carcinogens--Part B: biological agents. Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V; WHO International Agency for Research on Cancer Monograph Working Group (Cesarman E, Collaborator). Lancet Oncol 10:321-322, 2009.

Yao-Tseng Chen, MD, PhD

O Hofmann, OL Caballero, BJ Stevenson, YT Chen, T Cohen, R Chua, CA Maher, S Panji, U Schaefer, A Kruger, M Lehvaslaiho, P Carninci, Y Hayashizaki, CV Jongeneel, AJ Simpson, LJ Old, W: Hide: Genome-wide analysis of cancer/testis gene expression. Proc Natl Acad Sci USA 105:20422-20427, 2008.

LG Almeida, NJ Sakabe, AR Deoliveira, MC Silva, AS Mundstein, T Cohen, YT Chen, R Chua, S Gurung, S Gnjatic, AA Jungbluth, OL Caballero, A Bairoch, E Kiesler, SL White, AJ Simpson, LJ Old, AA Camargo, AT Vasconcelos: CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens. Nucleic Acids Res 37: D816-819, 2009.

PL Wagner, N Kitabayashi, YT Chen, A Saqi: Combined small cell lung carcinomas: genotypic and immunophenotypic analysis of the separate morphologic components. Am J Clin Pathol 131:376-382, 2009.

PL Wagner, YT Chen, RK Yantiss: Immunohistochemical and molecular features of sporadic and FAP-associated duodenal adenomas of the ampullary and non-ampullary mucosa. Am J Surg Pathol 32:1388-1395, 2008.

YT Chen, N Kitabayashi, XK Zhou, TJ Fahey III, T Scognamiglio: MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod Pathol 21: 1139-1146, 2008.

EC Kauffman, DA Barocas, YT Chen, XJ Yang, DS Scherr, JJ Tu: Differential Expression of KAI1 Metastasis Suppressor Protein in Renal Cell Tumor Histological Subtypes. J Urol 181:2305-2311, 2009.

YT Chen, M Hsu, P Lee, SJ Shin, P Mhawech-Fauceglia, K Odunsi, NK Altorki, CJ Song, BQ Jin, AJ Simpson, LJ Old: Cancer/testis antigen CT45: Analysis of mRNA and protein expression in human cancer. Int J Cancer 124:2893-2898, 2009.

S Gnjatic, LJ Old, YT Chen: Autoantibodies against cancer antigens. Methods Mol Biol 520:11-19, 2009.

Ruba Deeb, PhD

Tal N, Deeb RS, Hajjar DP, Gross SS: Protein 3-nitrotyrosine in complex biological samples: Quantification by HPLC-EC and emergence of proteomic approaches for unbiased identification of modification sites. Methods In Enzymol 441:1-17, 2008.

Francesca Demichelis, PhD

Hofer M, Kuefer R, Maier C, Herkommer K, Perner S, Demichelis F, Paiss T, Vogel W, Rubin MA, Hoegel J: Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer. Ca Res 69:640-6, 2009.

Demichelis F, Setlur SR, Beroukhim R, Perner S, Korbel JO, LaFargue CJ, Pflueger D, Pina C, Hofer MD, Sboner A, Svensson MA, Rickman DS, Urban A, Snyder M, Meyerson M, Lee C, Gerstein MB, Kuefer R, Rubin MA: Distinct genomic aberrations associated with ERG rearranged prostate cancer. Genes Chromo Ca 48:366-80, 2009.

Lora Ellenson, MD

Chekmareva M, Ellenson LH, Pirog EC: Immunohistochemical differences between mucinous and microglandular adenocarcinomas of the endometrium and benign endocervical epithelium. Int J Gynecol Pathol 27:547-554, 2008.

Park K, Bramlage M, Ellenson LH, Pirog EC: Immunoprofile of adenocarcinomas of the endometrium, endocervix, and ovary with mucinous differentiation. Appl Immunohistochem Mol Morphol 17:8-11, 2008.

Rana Shafiq-Hoda, MD

Thrall M, Russell D, Hoda RS: Use of the ThinPrep Imaging System does not result in higher ASC-US rates or subsequent referrals to colposcopy. Cytojournal 5:10, 2008.

Shrout J, Hoda RS, Mitas M, et al: b2microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients. Br J Cancer 98:1999-2005. Epub May 27, 2008.

Reed CE, Graham A, Hoda RS, Khoor A, Garrett-Mayer E, Wallace MB, Mitas M: A simple two-gene prognostic model for adenocarcinoma of the lung. J Thorac Cardiovasc Surg 135:627-34, 2008.

Blum C, Graham A, Hoda RS, Cole DJ, Carolyn Reed C, Mitas M: The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer. Int J Oncol 33:579-84, 2008.

Yakoushina TV, Medina IM, Hoda RS: "String of pearls" appearance of blue blobs in postmenopausal atrophy on ThinPrep Pap test. Diagn Cytopathol Feb 3, 2009.

Syed Hoda, MD

Cellini C, Hoda SA, Spigland N: Lupus-associated vasculitis manifesting as acute appendicitis. Pediatr Rheumatol 6:10-12, 2008.

Stephen Jenkins, PhD

Jenkins SG, Farrell DJ: A Significant Increase in Pneumococcal Macrolide Resistance in the USA. Emerg Infecs Dis 15:1260-1264, 2009.

Lee J, Patel G, Huprikar S, Calfee DP, Jenkins SG: Decreased susceptibility of polymyxin B during treatment for carbapenem-resistant Klebsiella pneumoniae infection. J Clin Microbiol 2009 March 4. [Epub ahead of print].

Endimiani A, Hujer AM, Perez F, Bethel CR, Hujer KM, Kroeger J, Oethinger M, Paterson DL, Adams MD, Jacobs MR, Diekema DJ, Hall GG, Jenkins SG, Rice LB, Tenover FC, Bonomo AR: Characterization of blaKPC-containing klebsiella pneumoniae isolates detected in different institutions in the Eastern United States. J Antimicrob Chemother 63: 427-437, 2009.

Lee J, Huprikar S, Jenkins SG: Are patients with POEMS syndrome at increased risk of Salmonella aortitis? Int J Infect Dis [Epub ahead of print] PMID: 18951055 Oct 22, 2008.

Jenkins SG: Antimicrobial susceptibility patterns in the United States and globally: findings of the TRUST and GLOBAL surveillance studies. Postgrad Med 120:5-7, 2008.

Calfee DP, Jenkins SG: Surveillance cultures to detect asymptomatic colonization with carbapenem-resistant Klebsiella pneumoniae among intensive care unit patients. Infect Control Hosp Epidemiol 10:966-968, 2008.

Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP: Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 29:1099-1106, 2008.

Endimiani A, Carias LL, Hujer AM, Bethel CR, Hujer KM, Perez F, Hutton RA, Fox WR, Hall GS, Jacobs MR, Peterson DL, Rice LB, Jenkins SG, Tenover FC, Bonomo RA: Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae possessing blaKPC in the United States. Antimicrob Agents Chemother 52:2680–2682, 2008.

Joan G. Jones, MD

Robinson BD, Sica GL, Liu YF, Rohan TE, Gertler FB, Condeelis JS, Jones JG: Tumor microenvironment of metastasis in human breast carcinoma: A potential prognostic marker linked to hematogenous dissemination. Clin Cancer Res 15, 2433-41,2009.

Daniel M. Knowles, MD

Chiu A, Nanaji NM, Czader M, Gheorghe G, Knowles DM, Chadburn A, Orazi A: The stromal composition of mast cell aggregates in systemic mastocytosis. Mod Pathol 2009 Apr 24. Epub ahead of print

Ehud Lavi, MD

Nizri E, Irony-Tur-Sinai M, Faranesh N, Lavon I, Lavi E, Weinstock M, Brenner T: Neuroinflammation suppression and improved cognitive function by the acetylcholinesterase inhibitor rivastigmine. J Neuroimmunol 203:12-22,2008.

Becher OJ, Souweidane M, Lavi E, Kramer K, Lis E, Marghoob AA, Khakoo Y: Large congenital melanotic nevi in an extremity with neurocutaneous melanocytosis. Ped Derm 26:79-82,2009.

Howard BM, Hofstetter C, Wagner PL, Muskin ET, Lavi E, Boockvar JA: Transformation of a low-grade pineal parenchymal tumor to secondary pineoblastoma. J Neuropathol Appl Neurobiol 35:214-217, 2009.

Attilio Orazi, MD

Venizelos I, Tatsiou Z, Papathomas TG, Orazi A: Visceral leishmaniasis in a rheumatoid arthritis patient treated with methotrexate. Int J Infect Dis 2008 Nov 19. Epub ahead of print

Bennett JM, Orazi A: Diagnostic criteria to distinguish hypocellular acute myeloid leukemia from hypocellular myelodysplastic syndromes and aplastic anemia: recommendations for a standardized approach. Haematologica 94:264-8, 2009.

Brahmanday GR, Gheorghe G, Jaiyesimi IA, Orazi A, Zekman R, Parikh R, Wills SM, Einhorn LH: Primary mediastinal germ cell tumor evolving into an extramedullary acute megakaryoblastic leukemia causing cord compression. J Clin Oncol 26:4686-8, 2008.

Fend F, Horn T, Koch I, Vela T, Orazi A: Atypical chronic myeloid leukemia as defined in the WHO classification is a JAK2 V617F negative neoplasm. Leuk Res 32:1931-5, 2008.

Orazi A, Germing U: The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features. Leukemia 22:1308-19, 2008. Review.

Barosi G, Mesa RA, Thiele J, Cervantes F, Campbell PJ, Verstovsek S, Dupriez B, Levine RL, Passamonti F, Gotlib J, Reilly JT, Vannucchi AM, Hanson CA, Solberg LA, Orazi A, Tefferi A: Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment. Leukemia 22:437-8, 2008.

Ganjoo KN, Moore AM, Orazi A, Sen JA, Johnson CS, An CS: The importance of angiogenesis markers in the outcome of patients with diffuse large B cell lymphoma: a retrospective study of 97 patients. J Cancer Res Clin Oncol 134:381-7, 2008.

Thiele J, Kvasnicka HM, Orazi A: Bone marrow histopathology In Myeloproliferative disorders. In Ayalew Tefferi & Richard T Silver: Myeloproliferative Disorders. Informa Healthcare LTD. New York, NY, 2008.

Orazi A, Czader, M: Chapter 15- Spleen. In Differential Diagnosis in Surgical Pathology,2nd edition, Paolo Gattuso, Vijaya Reddy, Odile David, Daniel J. Spitz, Meryl H. Haber Eds. W.B. Saunders (Elsevier) Philadelphia, PA, 2009

Orazi A, Vardiman JM: Diagnosis of Myelodysplastic Syndromes: criteria and Challenges. In, Myelodysplastic Syndromes: Pathobiology and Clinical Management, 2/e David P. Steensma, Ed. Informa Healthcare LTD, New York, NY. 2009

Edyta Pirog, MD

Hayes MP, Pirog EC, Hedrick Ellenson L: Chapter 29. Molecular gynecologic pathology in “Cell and tissue based molecular pathology”. Eds. Raymond Tubbs and Mark Stoler, Elsevier 2008.

Mark Rubin, MD

Beroukhim R, Brunet JP, Di Napoli A, Mertz KD, Seeley A, Pires MM, Linhart D, Worrell RA, Moch H, Rubin MA, Sellers WR, Meyerson M, Linehan WM, Kaelin WG Jr, Signoretti S: Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res 2009 May 26. [Epub ahead of print]

Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, Jänne OA, Balk SP, Mehra R, Han B, Chinnaiyan AM, Rubin MA, True L, Fiorentino M, Fiore C, Loda M, Kantoff PW, Liu XS, Brown M: Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell 138:245-56, 2009.

Lenkinski RE, Bloch BN, Liu F, Frangioni JV, Perner S, Rubin MA, Genega EM, Rofsky NM, Gaston SM: An illustration of the potential for mapping MRI/MRS parameters with genetic over-expression profiles in human prostate cancer. MAGMA 216:411-21, 2008.

David S. Rickman, PhD

Rickman DS, Pflueger D, Moss B, VanDoren VE, Chen CX, de la Taille A, Kuefer R, Tewari AK, Setlur SR, Demichelis F, Rubin MA: SLC45A3-ELK4 is a novel and frequent ETS fusion transcript in prostate cancer. Cancer Res 69:2734-8, 2009.

Audrey Schuetz, MD, MPH

Schuetz AN, Hughes RL, Howard RM, Williams TC, Nolte FS, Jackson D, Ribner BS: Outbreak of Legionella pneumophila serogroup 8 associated with a contaminated ice machine in a bronchoscopy suite. Infect Control Hosp Epidemiol 30:461-6, 2009.

Schuetz AN: Klebsiella pneumoniae carbapenemases (KPCs): When to suspect and how to detect them. 2008. Clinical Laboratory LabQ, LQ 09-17. Chicago, IL: ASCP Press; 125-132, 2009.

Cole JM, Schuetz AN, Hill CE, Nolte FS: Development and evaluation of a real-time PCR assay for the detection of Klebsiella pneumoniae carbapenemase genes. J Clin Microbiol 47:322-26, 2009.

Wang YF, Eaton ME, Schuetz AN, Nesheim SR: Human Immunodeficiency Virus, in Diagnostic Microbiology of the Immunocompromised Host. RT Hayden, K Carroll, YW Tang, and DM Wolk. Washington, DC: ASM Press 47-68, 2009.

Wayne Tam, MD, PhD

Mavrakis KJ, Zhu H, Silva RLA, Mills J, Teruya-Feldstein J, Lowe SW, Tam W, Pelletier J, Wendel, HG: Tumorigenic activity and therapeutic inhibition of Rheb GTPase. Genes & Dev 22:2178-2188, 2008.

Seidman M, Scognomiglio T, Hoda S: Cholesteroloma: A rare cause of indeterminate microcalcifications on mammography. The Breast J 15:303-304, 2009.

Tam W: The emergent role of microRNAs in molecular diagnostics of cancer. J Molec Diag 10: 411-414, 2008.

Iqbal J, Kucuk C, deLeeuw RJ, Srivastava G, Tam W, Geng H, Klinkebiel D, Christman, J, Patel K, Cao K, Shen L, Dybkaer K, Tsui I, Ali HH, Shimizu N, Au WY, Lam WL, Chan WC: Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia, 2009, e-published ahead of print.

Rhonda K. Yantiss, MD

RK Yantiss, M Goodarzi, XK Zhou, H Rennert, EC Pirog, BF Banner, YT Chen: Clinical, pathologic, and molecular features of early-onset colorectal carcinoma. Am J Surg Pathol 33:572-582, 2009.